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Cortisol Testing

The Cortisol test is also known as a Serum Cortisol test.

All you need to know about testing Cortisol levels with a laboratory test

  • What is the Cortisol test for?
  • How to test Cortisol?
  • What if Cortisol results are high?
  • What if Cortisol results are low?
  • Who should take the Cortisol (Stress) Blood test?
  • Is the Cortisol test kit safe to use?
  • Can I collect the sample at home with the Cortisol test kit from Vitall?
  • What should I do if my Cortisol test results are negative?
  • What should I do if my Cortisol test results are positive?
  • How do I interpret the results of my Cortisol test?
  • How do I use the Cortisol test kit?
  • How does the Cortisol test work?
  • What symptoms might indicate a need for a Cortisol test?
  • What conditions can a Cortisol test diagnose?
  • What is a Cortisol test?

Cortisol Testing UK Statistics 2026

Icon For Cortisol
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20.6% of people tested have Cortisol levels which are too high.

And 4.5% have levels that are too low.

402.8

Low
< 133

Normal
133 - 537

High
537 +

The average Cortisol result is 402.8 nmol/l
Note what is normal for you may differ for your age and sex.

Are you in the 75.0% with normal results?
Get Tested ›

What Is The Cortisol Test For?

Cortisol is your body's main stress hormone, influencing your mood, motivation, and fear.

The production and release of cortisol follows a circadian rhythm, highest in the early morning with several pulses throughout the day to the lowest levels in the evening.

This is called a diurnal rhythm and is clearly linked to daily activity patterns.

But cortisol is also released in high quantities in response to stress, to help the body respond appropriately, so high levels are a good indicator of this.

Although cortisol has an important role in driving your body's “fight-or-flight” instinct during a crisis, it also plays numerous other important roles on a daily basis. For example:

  • Managing the use of key nutrients like fats, proteins and carbohydrates
  • Controlling your sleep patterns
  • Regulating your blood pressure
  • Reducing inflammation
  • Increasing your blood sugar levels
  • Boosting energy levels to handle stressful events

Cortisol is produced in your adrenal glands, small organs at the top of your kidneys. The rate of cortisol production and release is carefully controlled by three different parts of the body communicating together. These are the pituitary gland, adrenal gland and the hypothalamus.

Testing for cortisol levels is useful for understanding adrenal gland function, particularly if someone suffers from hypertension (high blood pressure) - as elevated levels of cortisol contribute to hypertension.

How To Test Cortisol

By buying a laboratory test kit with professional nurse or clinic collection, you can accurately measure Cortisol for total reassurance.

Professional analysis in an accredited laboratory ensures rapid result delivery.

The Vitall Cortisol (Stress) nurse or clinic test kit includes a Cortisol test and is available for just £59.00.

Tests which include a Cortisol test:

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Take Control Of Your Health | Home Blood Testing Services

Cortisol (Stress) Test Kit

Cortisol (Stress) test kit
Cortisol (Stress) Home Test Kit UK

Cortisol (Stress) Test Kit

Check if your body is under stress or over-training

£59.00

View Full Details ›

What if Cortisol Results Are High?

Physical and emotional stress can increase cortisol levels. Levels can also rise during illness as part of the body’s response. Obesity, pregnancy, and some drugs—particularly oral contraceptives—may increase cortisol concentration in the bloodstream.

A high cortisol result can also be linked with conditions such as hyperthyroidism or Cushing's syndrome, and is often reviewed further to clarify the cause.

When high blood pressure occurs alongside a high cortisol level, the cortisol result may be relevant to understanding the cause of the high blood pressure.

A high cortisol level is not usually considered an acute problem needing immediate attention. Cortisol can vary from day to day, and multiple factors can contribute to a higher reading.

What if Cortisol Results Are Low?

Low blood cortisol can be caused by a number of conditions including hypothyroidism and certain drugs, including some steroid hormones.

It can also result from Addison's disease, where the adrenal glands stop producing sufficient amounts of the hormones cortisol and aldosterone. This can develop very slowly and may be difficult to identify because it is often associated with common, non-specific symptoms such as fatigue, weight loss, or nausea.

If cortisol levels remain low, further investigation is often carried out to determine the cause.

When interpreting a low cortisol result, the timing of the test is often considered. Cortisol levels vary throughout the day, so a truly low level is typically detected when the sample is taken first thing in the morning, usually at 8am. Natural day-to-day variation in cortisol can also differ in people who work shifts, and an 8am sample during a run of standard working days is often used for comparison. If the result remains low, it is sometimes followed up with further investigations to assess for Addison's disease.

Who Should Take This Test?

Measure your Cortisol levels and check if your body is under stress or over-training with a Cortisol (Stress) nurse or clinic finger-prick bloodtest kit

You get the convenient testing with the reassurance of professional clinical analysis. Your results are delivered quickly & securely online.

This Cortisol (Stress) Test is advised if you:

  • want the convenience of home testing without waiting for a GP appointment;
  • need a high quality, clinically accredited test done in a professional clinical laboratory.

Is the Cortisol test kit safe to use?

Yes, our cortisol test kit is designed with your safety in mind. The finger-prick test is minimally invasive and causes only minor discomfort. After collection, samples are safely packed in the kits before mailing.

Can I collect the sample at home with the Cortisol test kit from Vitall?

Yes, increasingly convenient and user-friendly, Vitall offers the option of self-collecting samples at home using a simple finger-prick test. The sample is then returned to the lab by post for expert analysis.

What should I do if my Cortisol test results are negative?

Negative results indicate that your cortisol levels are within the normal range. However, if you're still experiencing symptoms, you should consult with your healthcare provider for further assessment. It's possible other conditions or factors could be contributing to your symptoms.

What should I do if my Cortisol test results are positive?

Positive results indicate the presence of an abnormal level of cortisol in your blood. You should consult with a healthcare provider who can evaluate your results, consider your personal health history, and guide you towards the appropriate treatment or additional diagnostic testing.

How do I interpret the results of my Cortisol test?

Once analysed, your cortisol test results will be provided to you online in a clear, easy to understand format. Your result will be compared against a reference range for your age and sex and any abnormal result will be clearly explained. High cortisol levels may indicate conditions like Cushing syndrome, while low levels may suggest Addison's disease. We recommend discussing your results with a healthcare provider for professional advice.

How do I use the Cortisol test kit?

The kit comes with instructions that guide you on how to collect the blood sample. After collecting your sample, you package it as instructed, then send it back to the lab using the return envelope provided in the kit.

How does the Cortisol test work?

With Vitall, the cortisol test is a simple finger-prick test. You collect a small blood sample using the kit provided, then send it back to a UKAS accredited lab for analysis by a team of medical scientists.

What symptoms might indicate a need for a Cortisol test?

You might require a Cortisol test if you experience symptoms like unexplained weight loss, muscle weakness, fatigue, low blood pressure, skin changes (i.e., darkened skin patches), mood swings, or high blood sugar. These may indicate a cortisol imbalance in your body.

What conditions can a Cortisol test diagnose?

A Cortisol test may be used to help diagnose conditions related to the adrenal or pituitary glands, such as Addison's disease, Cushing's syndrome, adrenal insufficiency, and pituitary tumours. These conditions can affect the amount of cortisol your body produces.

What is a Cortisol test?

A Cortisol test, also known as Serum Cortisol test, is a diagnostic tool that measures the level of cortisol in your blood. Cortisol is a hormone that helps regulate your body's response to stress, maintain blood sugar levels, regulate metabolism, and support immune response.

Other Biomarkers Often Tested With Cortisol

Urine, swab or bood test. This test is available to buy online Cortisol

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