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Liver Function Home Test Kit

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Assess liver damage and your risk from liver disease with our simple and accurate fingerprick blood liver function home test kit.

Get liver function home test results delivered online, typically within 24 hours. Get rapid reassurance from an accredited clinical laboratory.

We Offer Seven Quality Assured Validated Laboratory Tests:


Alanine Aminotransferase (ALT)
Albumin (ALB)
Alkaline Phosphatase (ALP)
Bilirubin
Gamma-Glutamyl Transferase (GGT)
Globulins
Total Protein (TP)

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20.3% of people tested have Alanine Aminotransferase levels which are too high.

And 0.8% have levels that are too low.

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How Our Home Test For Liver Function Works

blood tests are fingerprick blood Liver Function test as little as 24 hours

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How Can I Test My Liver Function At Home?

You can test your Liver Function by carrying out the simple fingerprick blood sampling method.

Your blood sample can then be returned to the laboratory in a prepaid envelope for analysis.

Find out more about the Vitall range of at-home health tests and get accurate results delivered online.

How You'll Receive Your Test Results

Your Liver Function blood test results will be delivered quickly and securely to you in your personal online dashboard.
  • Each result is charted and clearly highlighted against normal ranges.
  • Any abnormal findings and possible reasons for this are fully detailed.
  • Receive an easy to understand overview of your health, fast.
  • Track your results over time to monitor lifestyle changes, treatments and behaviours.
  • Save up to 25% on repeat testing by subscribing when you checkout.

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Expert Blood Test Analysis in an Accredited Laboratory

Expert Liver Function Blood Test Analysis

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Liver function test results returned in as little as 24 hours.
Improved health and wellbeing home blood testing

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Assess liver damage and your risk from liver disease.

What's Tested In This Liver Function Home Test?

Seven biomarkers are measured to assess liver damage and your risk from liver disease.

Using a Fingerprick Blood Sample, this Liver Function Test Assesses:

Alanine Aminotransferase (ALT) is an enzyme mainly found in your liver. ALT is used by your body to break down food into energy, with levels in the blood normally low.

Following liver damage, the levels of ALT in your blood will rise making it a useful means to indicate liver problems.

Fluctuation of ALT levels is normal over the course of the day, and can also increase in response to strenuous physical exercise.

Albumin (ALB) is a protein produced by the liver and is the most abundant protein in the blood.

It transports components throughout the body, nourishes tissues & prevents blood vessel leakage.

Albumin is highly sensitive to liver damage so lower levels can indicate when the liver is damaged.

Alkaline phosphatase is an enzyme found in the human body in the kidneys, liver, bones and digestive system.

High levels of ALP typically result from liver damage or if you have increased bone cell activity.

Bilirubin is a natural waste product formed by the breakdown of the haemoglobin in your red blood cells. The liver then processes bilirubin before its removal from your body.

High levels of bilirubin in the blood can lead to yellowing of the skin (jaundice) and can indicate that liver damage is present.

The enzyme Gamma-Glutamyl Transferase (GGT) is found throughout the body, but it is most concentrated in your liver.

This makes a GGT blood test very useful helping to assess liver function and general health.

GGT levels are usually low, but can rise following liver damage. A GGT test is also particularly sensitive to detecting bile duct problems.

Globulins are a group term for proteins that make up nearly half of the total protein in your blood.  Globulins have a critical role in normal liver function, fighting infection and blood clotting.

Globulins are created by the immune system and the liver. The amount of globulins in your blood helps indicate many conditions such as liver damage, kidney diseases, autoimmune conditions or nutritional problems.

Proteins are absorbed from foods and are vital parts of all cells and tissues. They are used to build muscles, skin, blood, bones and cartilage as well as making enzymes, hormones and other essential chemicals.

The total protein test measures the blood levels of two different classes of proteins; albumin and globulin.

Abnormal levels can result from liver or kidney disorders.

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Why Take The Liver Function Test?

Our Liver Function home blood test kit checks multiple markers to measure normal liver function and to detect the presence of liver disease and other liver disorders. 

The liver plays a complex role in the body including the metabolism of drugs and toxic substances, management of blood sugar levels, vitamin storage and maintaining hormonal balance.

Fortunately, the liver has an incredible capacity to regenerate, and can respond well to healthy lifestyle changes.

Take control of your health without any of the inconvenience of going to the doctors with one of Vitall’s at-home blood tests.

Who Should Take The Liver Function Blood Test?

Assess liver damage and your risk from liver disease using a home fingerprick blood test kit.

You get the convenience of home testing with the reassurance of professional clinical analysis. Your results are delivered quickly & securely online.

This Liver Function Test is advised if you:

  • are anorexic or bulimic or suffer from another eating disorder;
  • are taking medications that cause toxic liver disease, which includes too much paracetamol, ibuprofen & aspirin;
  • drink alcohol regularly or are a binge drinker;
  • have family history of liver disease;
  • have had gallstones;
  • have had gastrointestinal disease (e.g. IBS);
  • take performance enhancing drugs, including steroids and creatine;
  • want the convenience of home testing without waiting for a GP appointment;
  • need a high quality, clinically accredited test done in a professional clinical laboratory.

Take a complete health check-up with Vitall.

£39

How Much Do Liver Function Tests Cost?

The Vitall liver function test is available online for just £39. Your home test kit will be dispatched by free first class post for delivery to your door.

For the best value testing you can also upgrade this liver function home test to tests which also measure other biomarkers, including:

When you checkout to buy your liver function test online we also offer additional options, including:

  • Upgrade to next day delivery of your home test kit for an additional £7.99.
  • Visit the Patient Reception in central London for just £25. Your liver function test sample can be collected by a qualified nurse for immediate analysis.
  • Have a nurse visit you to collect the sample for your liver function test, this is available within the M25 area for just £149.

Whichever option you choose at checkout, buying the best liver function test online in the UK with Vitall ensures high quality results from an accredited laboratory.

Take control of your health today with one of Vitall’s home blood tests.

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What Does The Liver Do?

Despite being the body’s largest solid organ and performing multiple vital functions, the purpose of the liver is commonly misunderstood. Among its primary functions, the liver has to manage macronutrients (carbohydrates, proteins, and fat), representing a critical hub for lipid and cholesterol metabolism; however, it’s capable of much more.[1]

The liver can be seen as the body’s factory: it takes the major components of your diet and turns them into a readily available energy source or integrates them into an accessible storage system. Upon feeding, the liver favours the conversion of glucose to glycogen, lipids to fatty tissue, and amino acids to proteins (albumin and globulins). Furthermore, the liver is essential for the intestinal absorption of lipids (including fat-soluble vitamins like vitamin A, D, E, and K)[1] and represents the primary site for the metabolism of various drugs[1][2] and body substances, such as bilirubin.[3]

The immune and endocrine systems are linked to the liver, too. It has its own immune cells (Kupffer cells)[4] and produces the hormones angiotensinogen (blood pressure regulator), hepcidin (controls iron metabolism), insulin-like growth factors (growth and metabolism controller), and thrombopoietin (promotes platelet production).[5] Finally, the liver regulates the production of blood coagulation factors, a vital function that allows the uninterrupted flow of blood to every organ.[6]

Given this complex functionality, assessing liver health requires a blood test, which can be conducted using a liver test at home.
 

What Is A Liver Function Test Home Kit?

Liver function is commonly tested through biochemical markers that provide a valuable and efficient overview of the organ; in other words, they are useful for the diagnosis and management of liver health or disease. 

Liver blood tests usually encompass alanine aminotransferase (ALT), gamma-glutamyl transferase (GGT), alkaline phosphatase (ALP), bilirubin, albumin (ALB), globulins, and total protein (TP). Liver function tests may exclude some of these markers while including others, such as aspartate aminotransferase (AST) or coagulation times (prothrombin time and partial thromboplastin time).[7]


In general, liver function tests at home shed some light on a few subjects:

  • Aminotransferases (ALT, GGT, AST) and ALP are useful for identifying liver injury. These markers are commonly found inside hepatocytes (liver cells), especially in the case of ALT.[8]
  • Hepatic proteins (albumin, globulins, total protein) are indirect markers of protein production in the liver.[8]
  • Bilirubin is a pigment derived from the breakdown of heme-containing proteins, such as haemoglobin. It is useful for determining hepatic clearance.[8]

Why Take A Liver Test At-Home?

Taking a liver function test at-home is not only a more convenient option but also can be a safer one. At-home blood testing opens the doors to patient-centric care, allowing people to take control of their health. Since its introduction, at-home testing has served an important role in early diagnosis and disease monitoring, enabling patients and doctors to act and plan in a timely manner.

A liver test home kit is excellent for a rapid health check or convenient monitoring. Viral hepatitis, alcohol-related liver disease, and non-alcoholic fatty liver disease are common conditions that are routinely investigated and followed with the help of liver function home tests. 

Some extrahepatic diseases can be suspected or supervised through these tests; for instance, bilirubin is commonly ordered in cases of suspected haemolytic anaemia[9] and albumin is employed during the assessment of nutritional risk in various populations, including the elderly and patients with cancer.[10]

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What Does The Normal Range Mean In Liver Function Tests?

The normal range is the term used for the range of liver function test values seen in 95% of the healthy population. The exact values may depend on your age, sex and the laboratory used for your liver function blood test.

  • Normal levels of albumin and globulins say a lot about good protein production in the liver, but they also mean that the body is receiving the right amount and variety of amino acids (from dietary protein) to build up albumin, globulins, and other hepatic proteins.[1]
  • Bilirubin is kept at a normal range thanks to the liver. A normal bilirubin value depends on good blood flow in and out of the liver, adequate liver function, and unobstructed bile flow out of the liver.[8]
  • Aminotransferases and ALP can be detected if liver cells are injured or destroyed. The levels detected in normal ranges are expected due to normal cellular turnover

However, these values do not blindly translate into good liver health without exceptions: if you are presenting signs, symptoms, or other findings that are attributable to liver disease, further medical assistance may be required.

What Happens If You Have Abnormal Liver Function?

Abnormal liver function, as reflected by altered liver function tests, means that the liver is:[11]

  • Unable to properly process and/or excrete bilirubin.
  • Unable to produce and maintain the free flow of bile.
  • Unable to properly synthesise proteins.
  • Unable to maintain hepatic cellular integrity.

However, having abnormal results do not necessarily signify liver disease. In some situations, the liver has to work harder than usual and some values may be abnormal. For example, many drugs (antibiotics, non-steroidal anti-inflammatory drugs, statins, antiepileptics, etc.) may slightly alter these values, especially aminotransferases and bilirubin.[11] To consider these changes benign, they must be mild, asymptomatic, and reversible.

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What Are The Signs And Symptoms Of Poor Liver Function?

a) Early warnings

  • Loss of appetite.
  • Unwanted or unexplained loss of weight.
  • Loss of muscular mass.
  • Feeling tired, weak, or ill most of the time.
  • Nausea and vomiting.
  • Tenderness, discomfort, or pain in the liver area (upper right side of the abdomen).
  • Sleeping disorders.
  • Reddened skin on the palms.

b) Symptoms of liver disease

  • Swelling of the lower limbs (legs, ankles, and feet) and abdomen (ascites).
  • Hair loss.
  • Yellowed skin and mucous membranes, such as the white of the eye or inside the mouth (jaundice).
  • Alteration of sexual characteristics, such as enlarged breasts in men and irregular menstrual cycles in women.
  • Lowered sexual desire (libido).
  • Itchy skin.
  • Frequent bruising.
  • Bleeding disorders, such as nosebleeds or prolonged bleeding.
  • Darkened urine and pale stools.

c) Severe signs and symptoms

  • Vomiting blood.
  • Shortness of breath.
  • Black stools.
  • Confusion.
  • High fever.
     

What Is Liver Disease?

Liver disease refers to any condition characterised by acute or chronic liver damage, making it unable to function properly. The presence of liver disease following abnormal liver function can often be identified using a liver home test kit.

It can be caused by a wide variety of factors, from alcohol consumption or unhealthy lifestyles to viruses or autoimmune disorders. As the damage persists over time, these conditions progress towards hepatic cirrhosis, which is marked by the formation of scar tissue (fibrosis).

The most common causes of liver disease are:[12]

  • Primary liver cancer, commonly a consequence of chronic liver disease.
  • Non-alcoholic fatty liver disease, which is related to obesity and metabolic syndrome.
  • Alcoholic-related fatty liver disease, caused by regular and excessive alcohol intake.
  • Viral hepatitis, caused by becoming infected with hepatitis-causing viruses, such as hepatitis A, B, C, D, and E.
  • Autoimmune liver disease, which occurs when the immune system mistakenly attacks the liver.
     

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How Does Alcohol Affect Your Liver Function?

Alcohol is one of the most important risk factors for disease and disability in general. This statement holds especially true for its main victim, the liver, which is the organ most responsible for metabolising ethanol. Alcohol, as well as its metabolites (by-products), act as hepatotoxins capable of directly damaging the liver. For example, acetaldehyde triggers inflammation and fibrosis; it is also capable of binding to proteins and DNA from liver cells, which may trigger immune responses against the hepatic tissues.[13]

Alcohol also damages the liver indirectly through multiple mechanisms. It acts synergistically with the human immunodeficiency virus (HIV) and hepatitis viruses B and C. Alcohol also promotes alcohol-related liver damage in patients with haemochromatosis and non-alcoholic fatty liver. The oesophagus, stomach, intestines, and pancreas are damaged by alcohol too, disrupting gastrointestinal function and, indirectly, damaging the liver.[13]

How Can I Keep My Liver Healthy?

It can take 20 years for chronic liver damage to produce detectable symptoms; considering this, action must be taken early. Check your health first using a liver blood test kit to highlight concerns. Most cases of liver disease can be prevented through accessible methods: hepatitis prevention and a healthy lifestyle.[14]

  • Viral hepatitis:
    • Hepatitis A vaccine is not routinely administered in the UK. It is recommended for people with chronic liver disease, high-risk workers, or those planning to travel to regions with high infection rates.[15]
    • Hepatitis B vaccine is included in the 6-in-1 vaccine offered to babies in the UK (August 2017 onwards). Your GP may vaccinate you if you consider you require the vaccine.[16]
    • Aside from vaccines, viral hepatitis is prevented by not sharing drug equipment, razors, and toothbrushes, using condoms during sex, and avoiding unlicensed tattoo or piercing studios.[17]
  • Lifestyle:[17]
    • Limit alcohol to 14 units per week. The fewer drinks the better.
    • Try to have at least 3 alcohol-free days in a row per week.
    • Exercise.
    • Have a balanced diet.
       

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How Can I Improve My Liver Health If It Is Inflamed Or Damaged?

Cirrhosis is commonly called “end-stage liver disease” and is mistakenly believed to be irreversible. While the scarring tissue will not disappear on its own, the liver may improve its functions once the damaging factor is removed.[12] Therefore, people with liver damage will also benefit from avoiding alcohol and having a healthy lifestyle. Preventing viral hepatitis is extremely important: patients with liver disease are recommended to get vaccinated against hepatitis A and B if they have not become infected in the past.

People with liver damage caused by hepatitis C, if indicated, may receive treatment with direct-acting antivirals (boceprevir, daclatasvir, dasabuvir, etc.). A study from the United Kingdom, which included patients with cirrhosis, found the overall curative efficacy of these treatments to be around 91%.[18] If you receive warfarin or other vitamin K antagonists, you should inform your physician before receiving direct-acting antivirals.[19]

When managing an existing condition or attempting to reverse damage, you can monitor improvements using a liver test at home.
 

Further Reading On Liver Function Tests At Home

  1. Trefts E, Gannon M, Wasserman DH. The liver. Curr Biol. 2017;27(21):R1147-R1151. doi:10.1016/j.cub.2017.09.019. Accessed 23 June 2021. Available from: https://doi.org/10.1016/j.cub.2017.09.019
  2. Le J. Drug Metabolism. Accessed 23 June 2021. Available from: https://www.msdmanuals.com/professional/clinical-pharmacology/pharmacokinetics/drug-metabolism#v50215772
  3. Hamoud AR, Weaver L, Stec DE, Hinds TD Jr. Bilirubin in the Liver-Gut Signaling Axis. Trends Endocrinol Metab. 2018;29(3):140-150. doi:10.1016/j.tem.2018.01.002. Accessed 23 June 2021. Available from: https://doi.org/10.1016/j.tem.2018.01.002
  4. Nguyen-Lefebvre AT, Horuzsko A. Kupffer Cell Metabolism and Function. J Enzymol Metab. 2015;1(1):101. Accessed 23 June 2021. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/pmc4771376/
  5. Cocciolillo, S., Sebastiani, G., Blostein, M., & Pantopoulos, K. (2020). Liver Hormones. Hormonal Signaling in Biology and Medicine, 425–444. doi: 10.1016/b978-0-12-813814-4.00018-3. Accessed 23 June 2021. Available from: https://doi.org/ 10.1016/b978-0-12-813814-4.00018-3
  6. Heinz S, Braspenning J. Measurement of Blood Coagulation Factor Synthesis in Cultures of Human Hepatocytes. Methods Mol Biol. 2015;1250:309-316. doi:10.1007/978-1-4939-2074-7_23. Accessed 23 June 2021. Available from: https://doi.org/10.1007/978-1-4939-2074-7_23.
  7. British Liver Trust. Liver blood tests (formally known as liver function tests - LFTs). Accessed 24 June 2021. Available from: https://britishlivertrust.org.uk/information-and-support/living-with-a-liver-condition/liver-blood-tests/
  8. Woreta TA, Alqahtani SA. Evaluation of abnormal liver tests. Med Clin North Am. 2014;98(1):1-16. doi:10.1016/j.mcna.2013.09.005. Accessed 23 June 2021. Available from: https://doi.org/10.1016/j.mcna.2013.09.005
  9. Phillips J, Henderson AC. Hemolytic Anemia: Evaluation and Differential Diagnosis. Am Fam Physician. 2018 Sep 15;98(6):354-361. PMID: 30215915.
  10. Almasaudi AS, Dolan RD, Edwards CA, McMillan DC. Hypoalbuminemia Reflects Nutritional Risk, Body Composition and Systemic Inflammation and Is Independently Associated with Survival in Patients with Colorectal Cancer. Cancers (Basel). 2020;12(7):1986. Published 2020 Jul 21. doi:10.3390/cancers12071986. Accessed 24 June 2021. Available from: https://doi.org/10.3390/cancers12071986
  11. Limdi JK, Hyde GM. Evaluation of abnormal liver function tests. Postgrad Med J. 2003;79(932):307-312. doi:10.1136/pmj.79.932.307. Accessed 27 June 2021. Available from: https://doi.org/10.1136/pmj.79.932.307
  12. Public Health England. Liver disease: applying All Our Health. Accessed 26 June 2021. Available from: https://www.gov.uk/government/publications/liver-disease-applying-all-our-health/liver-disease-applying-all-our-health
  13. Rocco A, Compare D, Angrisani D, Sanduzzi Zamparelli M, Nardone G. Alcoholic disease: liver and beyond. World J Gastroenterol. 2014;20(40):14652-14659. doi:10.3748/wjg.v20.i40.14652. Accessed 23 June 2021. Available from: https://doi.org/10.3748/wjg.v20.i40.14652
  14. British Liver Trust. The alarming impact of liver disease in the UK Facts and statistics. Accessed 26 June 2021. Available from: https://www.britishlivertrust.org.uk/wp-content/uploads/The-alarming-impact-of-liver-disease-FINAL-June-2019.pdf
  15. National Health Service (NHS). Hepatitis A vaccination. Accessed 26 June 2021. Available from: https://www.nhs.uk/conditions/hepatitis-a/vaccination/
  16. NHS. Hepatitis B vaccine. Accessed 26 June 2021. Available from: https://www.nhs.uk/conditions/vaccinations/hepatitis-b-vaccine
  17. British Liver Trust. Looking after your liver. Accessed 26 June 2021. Available from: https://britishlivertrust.org.uk/information-and-support/liver-health-2/love-your-liver/looking-after-your-liver/
  18. Macken L, Gelson W, Priest M, et al. Efficacy of direct-acting antivirals: UK real-world data from a well-characterised predominantly cirrhotic HCV cohort. J Med Virol. 2019;91(11):1979-1988. doi:10.1002/jmv.25552. Accessed 27 June 2021. Available from: https://doi.org/10.1002/jmv.25552
  19. Medicines and Healthcare products Regulatory Agency. Direct-acting antivirals to treat chronic hepatitis C: risk of interaction with vitamin K antagonists and changes in INR. Accessed 27 June 2021. Available from: https://www.gov.uk/drug-safety-update/direct-acting-antivirals-to-treat-chronic-hepatitis-c-risk-of-interaction-with-vitamin-k-antagonists-and-changes-in-inr
     

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All About Your Liver Function

A comprehensive guide to healthy liver function, the signs of liver disease and how a liver function test helps you identify issues.

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Expert Blood Test Analysis in an Accredited Laboratory

Expert Liver Function Blood Test Analysis

Evidence-based health checks are analysed in an accredited laboratory.
Rapid home blood tests from a professional laboratory

Get Rapid Blood Test Results

Liver function test results returned in as little as 24 hours.
Improved health and wellbeing home blood testing

Find Peace of Mind

Assess liver damage and your risk from liver disease.

£ 39