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Bicarbonate Testing (Bicarb)

The Bicarbonate test is also known as a Total CO2 or CO2 Content test.

All you need to know about testing Bicarbonate levels with a laboratory test

  • What is the Bicarbonate test for?
  • What if Bicarbonate results are high?
  • What if Bicarbonate results are low?
  • How long will it take to get the results of my Bicarbonate test?
  • Can I perform the Bicarbonate test on myself at home?
  • Can I take the Bicarbonate test if I'm feeling unwell?
  • Is there any preparation needed before taking the Bicarbonate test?
  • What should I do if my Bicarbonate test results are negative?
  • What should I do if my Bicarbonate test results are positive?
  • How do I interpret the results of my Bicarbonate test?
  • Can you explain how the Bicarbonate test works?
  • What symptoms can the Bicarbonate test help diagnose?
  • What conditions is the Bicarbonate test used for?
  • What exactly is the Bicarbonate test?

What Is The Bicarbonate Test For?

Bicarbonate (Bicarb) is both excreted and reabsorbed by your kidneys.

It serves to help maintain the acidity of your blood and tissues and interacts with other electrolytes (e.g. sodium, potassium, and chloride) to maintain optimum cellular chemistry.

The measurement of bicarbonate allows the estimation of your blood's acid-base balance and is an indicator of kidney performance.

How To Test Bicarbonate

By buying a laboratory test kit with professional nurse or clinic collection, you can accurately measure Bicarbonate for total reassurance.

Professional analysis in an accredited laboratory ensures rapid result delivery.

Tests which include a Bicarbonate test:

What if Bicarbonate Results Are High?

This result can be linked to metabolic alkalosis, which can occur when acid is lost from the body, often through vomiting and dehydration. This can lead to an increase in tissue pH.

It may also be related to conditions such as chronic obstructive pulmonary disease, where lung disease can result in increased acid in the blood, and the kidneys reabsorb more bicarbonate to help maintain normal acid–base balance.

Alkalosis (when blood pH is too high) can develop into severe medical problems if left untreated. This finding is often reviewed further to clarify the cause. Dizziness, difficulty breathing, and confusion are examples of symptoms that may be associated.

What if Bicarbonate Results Are Low?

Low bicarbonate can indicate difficulty maintaining the body’s acid–base balance. A wide range of medical conditions can be associated with low bicarbonate, including hormone disorders, chronic diarrhoea, kidney disease, and alcohol poisoning.

Because low bicarbonate is linked with many different conditions, this finding is often reviewed further to help clarify the cause. Acute symptoms that can occur in this context include dizziness, difficulty breathing, or confusion.

Who Should Take This Test?

Measure your Bicarbonate levels and with a nurse or clinic test kit

You get the convenient testing with the reassurance of professional clinical analysis. Your results are delivered quickly & securely online.

This Test is advised if you:

  • want the convenience of home testing without waiting for a GP appointment;
  • need a high quality, clinically accredited test done in a professional clinical laboratory.

How long will it take to get the results of my Bicarbonate test?

In most cases, you should expect to receive your lab analysed results within 24 hours after your sample arrives at the lab.

Can I perform the Bicarbonate test on myself at home?

No, this test is not suitable for self-collection due to the sample’s instability during postal transit, which could compromise the analysis results.

To address this, we offer a specialised mobile nursing service. A professional nurse will come to your home to collect the sample and carry out essential pre-processing procedures that guarantee the sample remains stable and viable for mailing.

Alternatively, you can choose to have the analysis conducted by visiting the London Patient Reception, where all processing and collection are handled on-site for optimal accuracy.

Can I take the Bicarbonate test if I'm feeling unwell?

If you're feeling significantly unwell or have severe symptoms, it's recommended to seek immediate medical attention. The Bicarbonate test is not an emergency diagnostic tool and results take time to be processed and returned.

Is there any preparation needed before taking the Bicarbonate test?

No specific preparation is required before taking a Bicarbonate test. If you're unsure about any instructions or if you're taking medications that may affect your results, it's best to contact your healthcare provider.

What should I do if my Bicarbonate test results are negative?

A negative result means your bicarbonate levels are lower than the normal range. This is seen in conditions such as kidney disease, metabolic acidosis or diabetic ketoacidosis. If your test results come back as lower than normal, it's important to consult with a healthcare provider for further evaluation.

What should I do if my Bicarbonate test results are positive?

Positive results could indicate a higher than normal level of bicarbonate in the blood, which can be an indication of conditions such as metabolic alkalosis, severe vomiting, or lung diseases. If your test results come back as being above normal, it is recommended that you consult with your healthcare provider for a detailed assessment.

How do I interpret the results of my Bicarbonate test?

The laboratory will analyse your blood sample and generate a report that shows whether your bicarbonate levels are within normal ranges. If your bicarbonate levels are too high or too low, it may indicate an imbalance in your body’s acid-base (pH) balance. Further interpretation and advice should be sought from a healthcare professional.

Can you explain how the Bicarbonate test works?

The Bicarbonate test measures the amount of bicarbonate, a form of carbon dioxide, in your blood. Bicarbonate acts to buffer or reduce the acidity in blood. You will usually prick your finger to get a blood sample which is analysed in a UKAS accredited laboratory to determine the levels of bicarbonate in your blood.

What symptoms can the Bicarbonate test help diagnose?

The Bicarbonate test can be helpful in diagnosing symptoms linked to acid-base imbalances, like confusion, fatigue, severe breathing difficulties, vomiting, increased heart rate, and tremors among others.

What conditions is the Bicarbonate test used for?

A Bicarbonate test is primarily used to detect and monitor electrolyte imbalances and acid-base balance issues in the body. It may be requested if you have symptoms related to conditions such as metabolic acidosis or alkalosis, kidney disease, respiratory issues or uncontrolled diabetes.

What exactly is the Bicarbonate test?

The Bicarbonate test, also referred to as Total CO2 or CO2 Content, is a medical test designed to evaluate the amount of bicarbonate, a form of carbon dioxide, in your blood. This can offer insight into the balance of acid and base in your body, which is essential for all cells to function properly.

Medical review

Doctors, Scientists & Experts Delivering Private Blood Testing Online

Dr. Shahzaib Ahmad MBBS, BSc, MRCP, FRCA, FFICM

Clinical Supervisor - Vitall|GMC 7495062|Profile

Dr Shahzaib Ahmad is a Consultant in Intensive Care Medicine with subspecialty experience in cardiac critical care and neurocritical care. He has extensive experience managing complex acute and cardiovascular conditions in hospital intensive care settings. Dr Ahmad supports Vitall in reviewing health content for clinical accuracy and alignment with current medical practice.

Reviewed on 03/02/2026

Next review due 03/02/2027

Review focus: Blood biomarkers, laboratory testing methodology, and biochemical interpretation.

This content has been reviewed for medical and scientific accuracy but does not replace advice from a qualified healthcare professional.

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